At every stage of drug and therapeutic development, comprehensive bioanalysis is crucial. It plays an essential role in consistently rendering reliable and accurate data in compliance to the strict set of scientific regulations to achieve the preclinical and clinical goals. However, bioanalytics has been labour intensive and technically challenging for a very long time. This has stirred the awareness and the need to bring in innovations that can improve and enhance the conventional methodologies in this space.
The advancements in the bioanalytical technologies for biotherapeutics have been immense in the last two decades, enabling to engineer biological molecules for medical needs like recombinant hormones, growth factors, monoclonal antibodies and vaccines. These generally comprise proteins or polypeptides of >40 amino acids whose active components and developed using biotechnology. The monoclonal antibodies are valuable tools that promise to provide targeted treatments owing to their high specificity. Besides, there has been an increased incidence of adopting Mesoscale devices and flow cytometry these days. Especially due to the virtue of serving as an efficient tool for biomarker analysis, flow cytometry has moved beyond the clinical diagnostic laboratories to regulated bioanalytical laboratories. This technique has extensive applications, including immunophenotyping, cell sorting, cell cycle analysis, intracellular calcium flux and many more. Further, newer techniques that are becoming increasingly prevalent are Immunogenicity analysis and cell-based neutralizing antibody measurements (Nab), Radioisotope analysis, Pharmacokinetic bioanalysis of small molecules and biologics, biochemistry—simulation assays, enzymatic activity, etc.
With more and more techniques coming into the space, the pharma and biotechnology firms are striving to raise the efficaciousness of bioanalytics and consequently accelerate the processes involved in the entire pipeline of drug development. To achieve this, they are seeking bioanalytical service providers to ensure quality, timelines as well as compliance. At this juncture, multiple companies are offering their innovative services to help meet the bioanalysis-related requirements for achieving their business goals while ensuring good public health and safety. To help navigate the top-in-line companies, Life Science Review has compiled a list of leading bioanalytical service firms at the top of their game. The enlisted companies can help unlock the potential of technologies to enhance the drug development process.
We present to you Life Science Review’s “Top 5 Bioanalytical Services Companies in UK - 2021.”